450 Lexington Ave is ideally located in the heart of Midtown, on 45th Street between Lexington and Park Avenue. 450 Lexington Ave is an impressive Class A building boasting over 910,000 square feet near Grand Central Station in Midtown Manhattan. Once a former post office, 450 Lexington Ave now houses multiple Fortune 500 companies, corporate headquarters, and prominent law and financial firms. The building features an atrium, expansive views of Manhattan, and is adjacent to Grand Central Station. Plus, 450 Lexington is near the 4, 5, 6, 7, and S subway lines, and Metro North trains.